Liar Liar Pants on Fire Big Pharma

Another example of their deception is carefully documented by Jonathan Leo and Jeffrey Lacasse in the December 2005 Public Library of Science Journal article entitled “Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature”, A news brief of the Canadian Medical Association Journal includes comments on this article by leaders in the field at ( A leading expert in the field admits, “Biological psychiatrists have looked very closely for a serotonin imbalance or dysfunction in patients with depression or obsessive compulsive disorder and, to date, it has been elusive,” says Dr. Wayne Goodman, Chair of the US Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee. Goodman was reacting to a recent article (December 2005, PLoS Medicine) about the growing body of medical literature that casts doubt on the “serotonin hypothesis.” Co-author Jonathan Leo, associate professor of anatomy at Lake Erie College of Osteopathic Medicine, says the FDA should prohibit SSRI manufacturers from making these claims.
GlaxoSmith-Kline (GSK), for example, claims ( that paroxetine (Paxil) can “help restore the balance of serotonin — which helps reduce the symptoms of anxiety and depression.” GSK officials refused to comment.
In 2003, Ireland’s drug regulator banned GSK from stating on its patient information leaflet that paroxetine “works by bringing serotonin levels back to normal.” Officials stated that “There is no scientific investigation to measure what are normal serotonin levels in the human brain receptors. As such, claiming that a particular medicinal product works by bringing serotonin levels back to normal is not accurate.”
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